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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects

Fig. 2

RA caused upregulation of Hox genes. a RNA-seq analysis of the dynamic expression of the four Hox clusters in cranial neural tissue of RA-induced mouse NTDs embryos from E8.5 to E10.5. b Dynamic expression of the 10 Hox genes in cranial neural tissue of RA-induced mouse NTDs embryos from E8.5 to E10.5. c Hox gene mRNA in cranial neural tissue of RA-induced mouse NTDs embryos was measured by RT-qPCR. Actb was used as control. Data are shown as the mean (SD; n = 3). *P < 0.05

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