Fig. 2
From: The distributions of protein coding genes within chromatin domains in relation to human disease
Fraction of genes associated with disease (ordinates) depending on the number of genes contained within the TADs (abscissas); the numbers have been aggregated for \(n \ge 6\). The lower the number of genes inside the TAD the higher fraction of the genes associated with disease. A p-value = 4 × \(10^{-54}\) from a Chi-square test, comparing the number of genes associated and non-associated with disease for the six TAD categories, has been obtained. The green dotted line represents the genome-wide fraction of genes associated with disease (0.354)