Table 1 Functionalities comparison between the SMART App and other tools
SMART App | methHC | Wanderer | MEXPRESS | MethSurv | |
|---|---|---|---|---|---|
Data source | TCGA | TCGA | TCGA | TCGA | TCGA |
Latest update | 2019 | 2014 | 2018 | 2019 | 2018 |
Genomic location visualization | Yes | No | Yes | Yes | No |
Pan-cancer methylation profile | Yes | Yes | No | No | No |
Differential analysis | Yes | Yes | Yes | Yes | Yes |
Correlation with other omics data | Yes | No | No | Yes | No |
Correlation with gene expression | Yes | Yes | Yes | Yes | Yes |
Correlation with transcript expression | Yes | No | No | No | No |
Cox regression analysis | Yes | No | No | No | Yes |
Survival analysis with custom threshold | Yes | No | No | No | Yes |
Hierarchical cluster analysis | No | Yes | No | No | Yes |
Methylation M value | Yes | No | No | No | No |