Fig. 2

BRM-involving cellular processes. BRM protein is involved in a variety of cellular processes both in healthy/normal and cancerous cells; for example, gene expression control, alternative splicing, cell cycle control, participating in hormonal response and miRNA transcription and signalling. In pathological situations, in cancer cells, BRM can leave the cell nuclei and migrate to cytoplasm or cell membrane, although specific effects of BRM in these locations are unknown