Fig. 3
From: Virtual methylome dissection facilitated by single-cell analyses
Co-methylation analysis to extract eigen-pCSM loci. a Heatmap of the methylation level of pCSM loci across brain methylomes. The methylation levels were represented by color gradient from blue (unmethylation) to red (full methylation). The color key in the right panel represents co-methylation modules. b Methylation profiles of the top five co-methylation modules. Each blue line represents the methylation level of pCSM loci across brain methylomes, the red lines represent the methylation level of eigen-pCSM loci picked by PCA analysis in each module, and 10% eigen-pCSM loci with the maximal loadings in PC1 were shown