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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Hemimethylation of CpG dyads is characteristic of secondary DMRs associated with imprinted loci and correlates with 5-hydroxymethylcytosine at paternally methylated sequences

Fig. 3

The maternally methylated secondary DMRs associated with Ndn and Peg12 display high levels of hemimethylation. a Methylation status at the Ndn DMR; F1 hybrid DNA derived from 7.5 dpc BxC embryos and 5 dpp BxC liver and brain. b Methylation status at the Peg12 DMR; F1 hybrid DNA derived from 5 dpp liver. Other details as described in Fig. 2. Data obtained from 7.5 and 14.5 dpc BxC embryos and adult BxC liver and brain are shown in Additional file 8: Figure S2. Reciprocal cross-data obtained from 13.5 dpc CxB embryos are shown in Additional file 10: Figure S4

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