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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Accurate ethnicity prediction from placental DNA methylation data

Fig. 4

Comparing PlaNET to existing methods to account for population stratification using HM450K data. For each cohort, principal components analysis was conducted on PlaNET using a model trained on all other cohorts. PlaNET’s principal components (PCs) were then compared to the PCs computed on sites from EPISTRUCTURE [9], Barfield’s method [8], and the 59 SNPs. a Amount of variance explained from a series of linear models where principal component “i” is a function of self reported ethnicity encoded as a dummy variable. b This was then repeated using AIMs coordinates 1 and 2 instead of ethnicity as the independent variable (n = 109)

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