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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

Fig. 5

Relationship between DNA methylation and H3K9me3 at ZFP57-binding sites in ES cells. a Relationship between loss of DNA methylation and loss of H3K9me3 at select ICRs, unique regions and transposable elements bound by ZFP57. 5′ LTR-IAP and IAPEY consensus regions were used as control. ns, not significant, *P < 0.05, **P < 0.01, ***P < 0.001; unpaired two-tailed t test. b Heat maps of ChIP signals for H3K9me3 in DNMT TKO (blue trace) and ZFP57 KO (red trace) ES cells at ZFP57-bound unique regions (left) and transposable elements (right)

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