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Table 1 Number of altered nucleosomes (in position, fuzziness and/or occupancy) upon histone depletion (in t::HHF2 cells) or cohesin inactivation (in scc1-73 cells) as compared to the profile of nucleosomes in wild-type cells

From: Crosstalk between chromatin structure, cohesin activity and transcription

  t::HHF2 scc1-73 t::HHF2 scc1-73
Altered nucleosomes 4431* 768 6151*
Position shift 319 35 389
Fuzziness change 1516 77 2093
Occupancy change 3989 703 5618
Occupancy increase 1304 375 2080
Occupancy decrease 2685 328 3538
  1. * The percentage of altered nucleosomes between t::HHF2 cells (6.68%) and scc1-73 t::HHF2 cells (9.28%) was statistically different according to a two-tailed Chi-square test (p < 0.001)