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Table 1 Number of altered nucleosomes (in position, fuzziness and/or occupancy) upon histone depletion (in t::HHF2 cells) or cohesin inactivation (in scc1-73 cells) as compared to the profile of nucleosomes in wild-type cells

From: Crosstalk between chromatin structure, cohesin activity and transcription

 

t::HHF2

scc1-73

t::HHF2 scc1-73

Altered nucleosomes

4431*

768

6151*

Position shift

319

35

389

Fuzziness change

1516

77

2093

Occupancy change

3989

703

5618

Occupancy increase

1304

375

2080

Occupancy decrease

2685

328

3538

  1. * The percentage of altered nucleosomes between t::HHF2 cells (6.68%) and scc1-73 t::HHF2 cells (9.28%) was statistically different according to a two-tailed Chi-square test (p < 0.001)
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Epigenetics & Chromatin

ISSN: 1756-8935