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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Crosstalk between chromatin structure, cohesin activity and transcription

Fig. 3

A lack of cohesin activity and histone depletion lead to similar occupancy changes in a subset of nucleosomes. a, c Overlap between IGR (a) or ORF (c) with altered nucleosomes in t::HHF2 or scc1-73 cells. b, d Overlap between IGR (b) or ORF (d) with either up- (increased occupancy) or down-nucleosomes (decreased occupancy) in t::HHF2 and scc1-73. e, f Overlap between up- (increased occupancy) or down-nucleosomes (decreased occupancy) in IGR (e) and ORF (f) in t::HHF2 and scc1-73 cells. Representative examples are shown; up- and down-nucleosomes are marked in green and red, respectively. The number of genomic regions (ad) or nucleosomes (e, f) in each case is indicated in parentheses. The probability of producing the given overlap if their distributions were random was generated using a hypergeometric test. The rate between the observed and expected frequencies is also shown

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