TY - JOUR AU - Hu, Shibin AU - Lv, Pin AU - Yan, Zixiang AU - Wen, Bo PY - 2019 DA - 2019/07/17 TI - Disruption of nuclear speckles reduces chromatin interactions in active compartments JO - Epigenetics & Chromatin SP - 43 VL - 12 IS - 1 AB - Nuclei of eukaryotes contain various higher-order chromatin architectures and nuclear bodies (NBs), which are critical for proper nuclear functions. Recent studies showed that active chromatin regions are associated with nuclear speckles (NSs), a type of NBs involved in RNA processing. However, the functional roles of NSs in 3D genome organization remain unclear. SN - 1756-8935 UR - https://doi.org/10.1186/s13072-019-0289-2 DO - 10.1186/s13072-019-0289-2 ID - Hu2019 ER -