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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: PRDM14 controls X-chromosomal and global epigenetic reprogramming of H3K27me3 in migrating mouse primordial germ cells

Fig. 4

Changes in both X-chromosomal and global levels of H3K27me3 in female PGCs require PRDM14 but are independent of each other. Relationship between X-chromosomal (bar graphs, % of PGCs per genotype) and global (pie charts, % of PGCs per genotype within each H3K27me3 spot/no spot sub-category) levels of H3K27me3 in PGCs from female embryos of different Prdm14 genotypes. Chi-square test was used to compare dependency of global of H3K27me3 upregulation on X-chromosomal removal for each Prdm14 genotype (n.s., not significant; Prdm14+/+ p = 0.956, Prdm14+/ p = 0.499, Prdm14/ p = 0.091)

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