Table 2 Methylation status of SSTR5-AS1 in LSCC tumor tissues
Groups | N | Methylation frequency | |||
|---|---|---|---|---|---|
Promoter | Exon 1 | ||||
n (%) | P | n (%) | P | ||
Age | |||||
 < 60 | 25 | 12(48.0) |  | 4(16.0) |  |
 ≥ 60 | 23 | 13(56.5) | 0.555 | 4(17.4) | 0.897 |
Gender | |||||
 Male | 46 | 24(52.2) |  | 8(17.4) |  |
 Female | 2 | 1(50.0) | 0.952 | 0(0.0) | 0.518 |
Smoking | |||||
 Negative | 10 | 4(40.0) |  | 2(20.0) |  |
 Positive | 38 | 21(55.3) | 0.390 | 6(15.8) | 0.751 |
TNM stage | |||||
 I + II | 19 | 6(31.6) |  | 3(15.8) |  |
 III + IV | 29 | 19(65.5) | 0.021 | 5(17.2) | 0.895 |
Pathological differentiation of tumor | |||||
 Well | 20 | 6(30.0) |  | 2(10.0) |  |
 Moderate | 16 | 10(62.5) |  | 3(18.7) |  |
 Poor | 12 | 9(75.0) | 0.028 | 3(25.0) | 0.525 |
LN metastasis | |||||
 Negative (N0) | 22 | 7(31.8) |  | 3(13.6) |  |
 Positive (N1/2/3) | 26 | 18(69.2) | 0.010 | 5(19.2) | 0.604 |