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Table 2 Methylation status of SSTR5-AS1 in LSCC tumor tissues

From: Aberrant methylation-mediated downregulation of lncRNA SSTR5-AS1 promotes progression and metastasis of laryngeal squamous cell carcinoma

Groups N Methylation frequency
Promoter Exon 1
n (%) P n (%) P
Age
 < 60 25 12(48.0)   4(16.0)  
 ≥ 60 23 13(56.5) 0.555 4(17.4) 0.897
Gender
 Male 46 24(52.2)   8(17.4)  
 Female 2 1(50.0) 0.952 0(0.0) 0.518
Smoking
 Negative 10 4(40.0)   2(20.0)  
 Positive 38 21(55.3) 0.390 6(15.8) 0.751
TNM stage
 I + II 19 6(31.6)   3(15.8)  
 III + IV 29 19(65.5) 0.021 5(17.2) 0.895
Pathological differentiation of tumor
 Well 20 6(30.0)   2(10.0)  
 Moderate 16 10(62.5)   3(18.7)  
 Poor 12 9(75.0) 0.028 3(25.0) 0.525
LN metastasis
 Negative (N0) 22 7(31.8)   3(13.6)  
 Positive (N1/2/3) 26 18(69.2) 0.010 5(19.2) 0.604