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Table 1 Protein expression and methylation status of SSTR5 in LSCC tumor tissues

From: Aberrant methylation-mediated downregulation of lncRNA SSTR5-AS1 promotes progression and metastasis of laryngeal squamous cell carcinoma

Groups N Protein expression Methylation frequency (promoter) Methylation frequency (Exon 1)
n (%) P n (%) P n (%) P
Age
 < 60 25 9 (36.0)   4 (16.0)   13 (52.0)  
 ≥ 60 23 7 (30.4) 0.683 5 (21.7) 0.611 14 (60.9) 0.536
Gender
 Male 46 15 (32.6)   9 (19.6)   26 (56.5)  
 Female 2 1 (50.0) 0.610 0 (0.0) 0.488 1 (50.0) 0.856
Smoking
 Negative 10 4 (40.0)   2 (20.0)   5 (50.0)  
 Positive 38 12 (31.6) 0.615 7 (18.4) 0.909 22 (57.9) 0.654
TNM stage
 I + II 19 10 (52.6)   3 (15.8)   7 (36.8)  
 III + IV 29 6 (20.7) 0.022 6 (20.7) 0.671 20 (68.9) 0.028
Pathological differentiation of tumor
 Well 20 9 (45.0)   3 (15.0)   8 (40.0)  
 Moderate 16 5 (31.3)   3 (18.7)   10 (62.5)  
 Poor 12 2 (16.7) 0.252 3 (25.0) 0.782 9 (75.0) 0.128
LN metastasis
 Negative (N0) 22 11 (50.0)   4 (18.2)   8 (36.4)  
 Positive (N1/2/3) 26 5 (19.2) 0.024 5 (19.2) 0.926 19 (73.1) 0.011