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Fig. 8 | Epigenetics & Chromatin

Fig. 8

From: MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL

Fig. 8

TET1, TET2, and MYC target genes overlap. Overlap between DEGs upon TET1 KD and ectopic TET2 expression in human T-ALL cells (CCRF-CEM), and previously identified MYC target genes, obtained from the Molecular Signatures Database (MSigDB) [35,36,37]. The intersection between genes is displayed as Venn diagram. Gene names are listed in Additional file 3

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Epigenetics & Chromatin

ISSN: 1756-8935