TY - JOUR AU - Poole, Candace J. AU - Lodh, Atul AU - Choi, Jeong-Hyeon AU - van Riggelen, Jan PY - 2019 DA - 2019/07/02 TI - MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL JO - Epigenetics & Chromatin SP - 41 VL - 12 IS - 1 AB - While aberrant DNA methylation is a characteristic feature of tumor cells, our knowledge of how these DNA methylation patterns are established and maintained is limited. DNA methyltransferases and ten-eleven translocation methylcytosine dioxygenases (TETs) function has been found altered in a variety of cancer types. SN - 1756-8935 UR - https://doi.org/10.1186/s13072-019-0278-5 DO - 10.1186/s13072-019-0278-5 ID - Poole2019 ER -