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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

Fig. 4

Functional analysis of DARs at DEGs. a, b Heat maps show ATAC-seq read densities and gene expression by RNA-seq for DEGs in the 6 clusters of peaks in Path1 (lens fiber cell differentiation path) (a) and 3 clusters of Path2 (lens epithelium maturation path) (b). c, d Dot plots show enriched GO terms and TF motifs for the DAR clusters of Path1 and Path2. The dot color represents –log10(FDR) or –log10(p value), and the dot size represents number of regions enriched in the GO terms or percentages of peaks with the motifs

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