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Fig. 11 | Epigenetics & Chromatin

Fig. 11

From: Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

Fig. 11

Examples of clusters of predicted cis-regulatory sites in Mip promoter and its proximal and distal enhancers. a Mip locus and its promoter and two enhancers (− 0.6 kb proximal and − 8 kb distal). b Experimentally validated (Pitx3 and Sp1) and predicted (Hsf4, MafK, Smad, and Sox) grammar of the Mip promoter and enhancers. M, H, and C show DNA sequences from mouse, human, and cow, respectively

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