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Fig. 10 | Epigenetics & Chromatin

Fig. 10

From: Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

Fig. 10

Examples of clusters of predicted cis-regulatory sites in Foxe3 and Prox1 enhancers. a Foxe3 locus including its 5′-enhancer (− 3 kb). b Prox1 locus including its 3′-distal enhancer (− 23 kb). c Experimentally validated (Pitx3) and predicted (Sox2 and Tfap2a) grammar of the Foxe3 enhancer. d Experimentally validated (Pax6) and predicted grammar (Sox and AP1/Jun) of the Prox1 enhancer. M, H, and C show DNA sequences from mouse, human, and cow, respectively

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