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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing

Fig. 5

NET-seq results. a A schematic representation of the NET-Seq Illumina library preparation. b Metagene analysis of NET-Seq at different genomic regions for wild type (WT) and PARP knockdown (KD) cells reveals shortened transcripts (b: orange lines—WT, red lines—KD) and lengthened transcripts (c): purple and violet lines—WT, blue lines–KD). d Visualization of gene ontology: biological process categories of PARP1 effecting of RNAPII activity

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