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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

Fig. 2

Allele-specific expression of imprinted genes in mouse in vivo and in vitro pluripotent states. a Allelic bias in expression of known imprinted genes plotted by the percentage of B6 as compared to the total coverage of B6 and DBA2 per gene. Within individual panels, the left axis represents expression from the DBA2 (paternal) allele, the right axis represents expression from the B6 (maternal) allele, and the middle axis represents equal biallelic expression. The individual replicas of all samples are included in the graph, but not individually labeled. The graph only includes data points of genes for which we obtained sufficient coverage to calculate allelic bias, explaining the variable number of data points between genes or the complete lack of data points for some genes in either of the cell lines or the embryonic tissue. “P” = paternally expressed; “M” = maternally expressed. b Similar to a, showing allelic expression of imprinted genes during differentiation of ESCs toward embryoid bodies (left panel) or NPCs (right panel)

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