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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Coordination between TGF-β cellular signaling and epigenetic regulation during epithelial to mesenchymal transition

Fig. 2

Changes of cell morphology and expression of given proteins after adding TGF-β. a Cells show fibroblast-like features over the stimulation time-course, indicating a mesenchymal phenotype switch. b WB results indicate that Smad2 was phosphorylated in 5 min after adding TGF-β, which is a direct target of TGF-β signaling and should be a nice positive control. c Expression changes of given proteins quantified by WB and MS, respectively. Data are means ± SD (standard deviation) of triplicates. As expected, epithelial marker protein E-cadherin and mesenchymal marker protein N-cadherin were down-regulated and up-regulated, respectively

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