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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Coordination between TGF-β cellular signaling and epigenetic regulation during epithelial to mesenchymal transition

Fig. 1

Experimental design for study of cross talk between TGF-β cellular signaling and epigenetic regulation during EMT. a TGF-β was added to induce EMT in NMuMG cells, and expressions at proteome, phosphoproteome and histone PTMs level were quantified, respectively. The different curves implied distinct regulation patterns during EMT programming. b Workflow for quantitative and time-resolved analysis of (phospho)proteomes using triple SILAC labeling. Two experiments with biological triplicates were performed with 0 min as a common time point

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