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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers

Fig. 5

Blood DMRs distinguish patients with WD from controls. a WGBS-derived DMRs differentiating WD from both HC and DC, but not DC from HC, were identified (WD n = 40, HC n = 12, DC n = 20). b Heatmap of HC, WD, NAFLD, and PSC blood using methylation in WD-specific blood DMRs. Percent methylation for each sample relative to the mean methylation at each DMR is plotted. c Principal component analysis using methylation in WD-specific blood DMRs. Ellipses show 95% confidence intervals

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