Fig. 5

Preconception paternal alcohol exposure associates with long-term alterations in immune signaling within the offspring. Abundance of the inflammatory cytokines IL1B, IL6, INFg and TNFa in the a–d liver, e–h pancreas and i plasma of 8-week-old offspring sired by ethanol-exposed and control males (n = 8). Data analyzed using a two-way ANOVA followed by Sidak post hoc analysis. Error bars represent SEM *p < 0.05, **p < 0.01 and ***p < 0.001 (comparisons between alcohol and control preconception treatments)