TY - JOUR AU - Fedotova, Anna AU - Clendinen, Chaevia AU - Bonchuk, Artem AU - Mogila, Vladic AU - Aoki, Tsutomu AU - Georgiev, Pavel AU - Schedl, Paul PY - 2019 DA - 2019/01/03 TI - Functional dissection of the developmentally restricted BEN domain chromatin boundary factor Insensitive JO - Epigenetics & Chromatin SP - 2 VL - 12 IS - 1 AB - Boundaries in the Drosophila bithorax complex delimit autonomous regulatory domains that activate the parasegment (PS)-specific expression of homeotic genes. The Fab-7 boundary separates the iab-6 and iab-7 regulatory domains that control Abd-B expression in PS11 and PS12. This boundary is composed of multiple functionally redundant elements and has two key activities: it blocks crosstalk between iab-6 and iab-7 and facilitates boundary bypass. SN - 1756-8935 UR - https://doi.org/10.1186/s13072-018-0249-2 DO - 10.1186/s13072-018-0249-2 ID - Fedotova2019 ER -