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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs

Fig. 6

Promoter activity modeling distinguishes gene activities in DMG samples. a Scatterplot comparing the promoter scores of VUMC-10 and SU-DIPG-XIII cell culture samples. Locations of the promoters of several cell signaling components implicated in tumor growth are indicated as colored circles. b Scatterplot comparing the promoter scores of VUMC-10 cell culture (C.C.) and xenograft (Xeno.) samples. Only 388 promoters have a ≥ twofold difference in activity modeling scores between these samples. c Hierarchically clustered matrix of Spearman correlations of promoter chromatin scores between VUMC-10 (V) and SU-DIPG-XIII (S) cells grown in cell culture (C.C.) or as xenografts (Xeno.), as well as H1 and K562 cells

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