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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation

Fig. 1

Ezh2 splicing is differentially regulated during meiosis and mitosis. a Schematic structure of the mouse Ezh2 gene and protein. Removal of exon 14 causes the disruption of the CXC domain. b RT-PCR analysis of alternative Ezh2 transcripts in mouse testis at different ages, tissues, embryos, and cell lines. c Quantitation of Ezh1 and Ezh2 transcripts during testis development by qPCR analysis. d Quantitation of the transcription of PRC2 core components by qPCR analysis. e Quantitation of Ezh1 and Ezh2 transcripts during the cell cycle progression. f Western blot analysis of PRC2 core components during the cell cycle progression

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