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Table 3 Clinical information on samples assigned to cluster 1 and cluster 2 obtained by neutrophil-specific CpGs

From: DNA methylation profiling of acute chorioamnionitis-associated placentas and fetal membranes: insights into epigenetic variation in spontaneous preterm births

Neutrophil-specific

Cluster 1 (n = 22)

Cluster 2 (n = 20)

p value

aCA status (aCA/total)

17/22

5/20

< 0.005

Fetal sex (M/total)

15/24

9/20

ns

Gestational age, weeks

28.3–36

28–36.7

ns

Maternal age, years

21.2–43.9

20.4–43.5

ns

Fetal birth weight (SD)

− 1.14 to 1.58

− 2.46 to 0.73

ns

  1. p values are calculated by Wilcoxon–Mann–Whitney rank sum test for continuous variables, Fisher’s exact test for fetal sex and aCA status
  2. ns non-significant