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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: DNA methylation profiling of acute chorioamnionitis-associated placentas and fetal membranes: insights into epigenetic variation in spontaneous preterm births

Fig. 4

Differentially methylated CpG sites in the chorionic villi comparison of aCA cases to non-aCA cases. Box plots of DNA methylation for four representative CpGs sites that are either hypermethylated or hypomethylated in the aCA cases compared to non-aCA cases in chorionic villi. These sites are among 24/36 sites that showed similar trends in DNAm for the multiple immune cell types (eosinophil, neutrophil, monocytes, and lymphoid) as aCA chorionic villi cases. For example, when aCA cases were hypomethylated compared to non-aCA cases, immune cells were also hypomethylated compared to non-aCA

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