Fig. 1From: The methylome of the marbled crayfish links gene body methylation to stable expression of poorly accessible genesConservation of Dnmt1, Dnmt3 and Tet in marbled crayfish. Genome annotation revealed the presence of a DNA methylation system consisting of single homologs for Dnmt1 (a), Dnmt3 (b) and Tet (c), respectively. Shown are comparisons of virtually translated protein sequences with three reference organisms: Daphnia pulex, Apis mellifera and Homo sapiens. Numbers in brackets represent accession numbers. Conserved domains are shown as colored boxes. Dnmt1: orange—DMAP1-binding domain, dark blue—replication foci domain, light blue—CXXC zinc finger domain, light green—bromo adjacent homology domain, purple—catalytic domain. Dnmt3: pink—PWWP domain, dark green—zinc finger domain, purple—catalytic domain. Tet: red—catalytic domain, light blue—CXXC zinc finger domain. d Expression of Dnmt1, Dnmt3 and Tet during marbled crayfish development. mRNA expression levels are indicated relative to the TBP (TATA-box-binding protein) housekeeping gene. Bars indicate standard deviations from at least three independent measurements. E: embryonic stages; J: juvenile stages. e mRNA levels of Dnmt1, Dnmt3 and Tet in various adult marbled crayfish tissues (hepatop. hepatopancreas, abd. musc. abdominal musculature)Back to article page