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Table 1 The number of DMRs identified in tumours (n = 3 per group) formed from depleted cells compared with non-depleted cells

From: Modulation of mitochondrial DNA copy number in a model of glioblastoma induces changes to DNA methylation and gene expression of the nuclear genome in tumours

Comparisons

p ≤ 0.05

p ≤ 0.01

p ≤ 0.001

Adj. p ≤ 0.05

GBM50 versus GBM100

8980 (16.85%: 83.15%)

1135 (10.57%: 89.43%)

124 (7.26%: 92.74%)

–

GBM3 versus GBM100

4940 (34.76%: 65.24%)

597 (41.88%: 58.12%)

36 (44.44%: 55.56%)

–

GBM0.2 versus GBM100

51,366 (11.25%: 88.75%)

34,060 (3.66%: 96.34%)

16,565 (2.14%: 97.86%)

143 (21.68%: 78.32%)

  1. The ratio of hyper- and hypo-methylated DMRs (expressed as percentages) is shown in brackets
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Epigenetics & Chromatin

ISSN: 1756-8935