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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions

Fig. 4

Gene expression levels versus promoter interactions in the A compartment. a Genes in compartment A were partitioned into three groups according to their expression levels. For each group, the distribution of genes over bins of number of promoter interactions, inferred from Hi–C data, is shown. p value was calculated using Wilcoxon’s test comparing the distributions in the least and most abundant expression groups. b Genes in compartment A were partitioned into three groups according to the number of interactions their promoters are engaged in, and the distributions of gene expression levels were compared (p value is for Wilcoxon’s test comparing the group of genes with 0 interactions to the genes with at least one interaction). c, d The same analysis as in B and A, respectively, but here using promoter interactions derived from RNA PolII ChIA-PET data in the GM12878 cell line. e The same analysis as in d, but using CTCF ChIA-PET data (in GM12878)

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