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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions

Fig. 2

a Association between dynamic A/B compartmentalization and differential gene expression in the comparison between the GM12878 and K562 cell lines (AB: the set of genes that are located in compartment A in GM12878 and B in K562; BA: genes located in compartment B in GM12878 and A in K562). Genes in AB have significantly higher expression in GM12878, while genes in BA have higher expression in K562 (p value calculated using Wilcoxon’s test). b Correlation between the change in the magnitude of PC1 and change in expression level in the comparison between GM12878 and K562 cell lines. The range of ΔPC1 was divided into six bins, and the distribution of fold change in gene expression was calculated for each bin. Below each boxplot, the mean value of ΔPC1 in that bin and the number of genes assigned to it are indicated

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Epigenetics & Chromatin

ISSN: 1756-8935