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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Perturbed maintenance of transcriptional repression on the inactive X-chromosome in the mouse brain after Xist deletion

Fig. 3

IF for a H3K27me3 and b H2AK119ub1 in the brain of animals without (control) and with Xist deletion (mutant). Punctate nuclear staining for both H3K27me3 and H2AK119ub1 is abolished by Xist deletion. c Percentage of cells in the brain with punctate staining for the indicated histone modification is severely reduced in animals lacking Xist (n = 3 for each group, error bar indicates SD, **p < 0.01, ***p < 0.001, Student’s t test)

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