Fig. 6
Sequence analyses differentiate Dependent and Independent sites. a Nucleotide density and b conservation scores display differences between Groups A, C, and D and between Dependent and Independent classes of CRX sites in each Group. Both are calculated in 20-bp windows +/− 1 kb from center of CRX peak. (Two-way ANOVA with Tukey multiple comparison testing; ****p < 0.0001) c, d CRX affinity scores, as defined by BEEML algorithm are displayed for two DNA/protein ratios (μ values). (Red line denotes median; Wilcoxon rank sum test, *p < 0.05, **p < 2.2 × 10−5, ***p < 2.2 × 10−10, ****p < 2.2 × 10−16)