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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

Fig. 4

CRX is only required for activity and remodeling of a subset of Group A local regulatory sites. a Plots display read density of DNase I experiments centered on CRX-binding site of Dependent and Independent Group A sites. b Analysis of RNA-seq of nearest gene to each peak, displayed as boxplot of normalized RPKM values at P2 and P21 in WT and P21 in Crx/−. (Wilcoxon rank sum test, paired; *p < 0.05, **p < 2.2 × 10−5, ***p < 2.2 × 10−10, ****p < 2.2 × 10−16)

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