Fig. 1

CRX binds a subset of active regulatory sites in the rod photoreceptor. a Browser track displays ATAC-seq, DNase I, and CRX ChIP-seq read depth. (Scale bar 5 kb) b Venn diagram depicting number of CRX ChIP-seq-defined binding sites that overlap with regulatory sites defined by ATAC-seq. (c, d) Meta-gene plots of all genes expressed in P21 WT and Crx−/− retinas, ordered by [log2] fold-change (as detailed on left). Black dots represent the center of ATAC regulatory site relative to TSS of c all ATAC peaks and of d only the subset bound by CRX. Histograms on X and Y axes display density and distribution of the data points