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Table 1 Effects on gene expression of the methylation status and the relative distance of the CpGs inside the four transcription factor binding motifs enriched in the first introns

From: Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species

Tissue Factors SS d.f. F value p value
Muscle Relative distance 5.18 1 1.872 0.173
Methylation status 10.76 1 3.885 0.051
Interaction of relative distance with methylation status 17.35 1 6.264 0.013
Residuals 387.65 140   
Testis Relative distance 7.31 1 1.855 0.176
Methylation status 121.86 1 30.900 0.000
Interaction of relative distance with methylation status 22.8 1 5.781 0.018
Residuals 540.28 137   
  1. The effects were tested using analysis of covariance, and the statistically significant ones are shown in italics
  2. d.f. degrees of freedom, SS sums of squares
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Epigenetics & Chromatin

ISSN: 1756-8935