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Table 1 Relative basal abundance of discrete H4 PTMs

From: The histone H4 proteoform dynamics in response to SUV4-20 inhibition reveals single molecule mechanisms of inhibitor resistance

 

SUM159 cells (%)

MCF7 cells (%)

Nα-ac

98.2 ± 0.6

96.4 ± 0.9

S1ph

0.1 ± 0.0

0.2 ± 0.1

R3me1

0.2 ± 0.1

0.2 ± 0.1

K5ac

2.0 ± 0.4

3.2 ± 0.7

K8ac

1.7 ± 0.6

1.1 ± 0.2

K12ac

6.0 ± 1.4

3.3 ± 0.6

K16ac

40.6 ± 2.4

35.8 ± 0.9

K20me1

12.2 ± 1.3

7.7 ± 0.6

K20me2

76.2 ± 1.6

78.7 ± 1.3

K20me3

8.3 ± 1.1

10.1 ± 0.7

K20un

3.3 ± 1.1

3.4 ± 0.8

K31ac

7.2 ± 1.1

7.5 ± 0.8