Skip to main content
Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: The histone H4 proteoform dynamics in response to SUV4-20 inhibition reveals single molecule mechanisms of inhibitor resistance

Fig. 3

H4K20me2 and H4 acetylation are anti-correlated in abundance. a The effect of SUV4-20 inhibition on discrete H4{K20me2} and total level of H4 acetylation. b The effect of SUV4-20 inhibition on discrete H4 acetylations in SUM159 and MCF7 cells. c Increased discrete H4 acetylation and d binary combinations of H4 acetylation upon SUV4-20 inhibition recover within 15 min after removal of SUV4-20 inhibitor in SUM159 cells. *p < 0.05; **p < 0.01; ***p < 0.001, p < 0.0001. Error bars in a, b, c, d represent standard error from three biological replicates

Back to article page