Fig. 1

SUM159 and MCF7 cells differ in basal histone H4 epigenetic states. a Flowchart of experimental setup, b selected histone PTMs of the N-terminal tail of H4, c comparison of discrete H4 acetylations between SUM159 and MCF7 cells. *p < 0.05. d Discrete level of K20 methylation states are similar between the selected cell lines. e Volcano plot of proteoforms differences between these two cell lines. Data points in the gray dashed squares indicate infinity fold change. Error bars in c and d represent standard error from three biological replicates