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Table 4 Partial list of TFBS motifs enriched in AREs at different stages of hematopoiesis

From: Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

Transcription factor

ERY-specific AREs

MEG-specific AREs

LSK (active)

LSK (poised)

CMP

CFU-E

LSK (active)

LSK (poised)

CMP

CFU-MK

AP-1

     

0.005

< 0.0001

< 0.0001

BACH1

   

0.001

    

BATF

     

0.005

0.0001

0.002

CEBP

      

0.001

0.001

CHOP

      

0.0001

0.001

NF-E2

  

0.02

0.0002

    

EHF

    

0.0001

0.005

< 0.0001

< 0.0001

ELF1

    

0.0001

 

< 0.0001

< 0.0001

ERG

    

0.0009

 

< 0.0001

< 0.0001

ETS

    

0.0001

0.0003

< 0.0001

< 0.0001

ETS1

    

0.0008

 

< 0.0001

< 0.0001

PU.1

    

0.0148

0.0039

< 0.0001

< 0.0001

SpiB

    

0.0004

0.0017

< 0.0001

< 0.0001

FLI1

      

< 0.0001

< 0.0001

IRF1

    

0.0138

0.0017

< 0.0001

< 0.0001

IRF2

    

0.0052

 

0.0001

0.0005

IRF8

    

0.0459

   

RUNX1

      

0.0004

0.002

RUNX2

      

0.002

0.01

GATA1

  

0.03

0.01

    

GATA2

  

0.03

0.01

    

KLF3

     

0.0281

  

SP1

      

0.04

 
  1. Benjamini-adjusted q-value for the enrichment score is reported
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Epigenetics & Chromatin

ISSN: 1756-8935