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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

Fig. 6

Transcriptional and epigenetic features illustrating different modes of regulation. a Induction of expression and AREs at Slc4a1, Bloodlinc, and Slc25a39. RNA-Seq data (left panel) are shown for each pair of replicates only for transcription of the minus strand (and thus RNA from Rundc3a is not shown). ATAC-Seq patterns (central panel) are shown for each pair of replicates. Histone modifications (right panel) are shown as single determinations, although some are available as replicates. b Retention of expression and AREs and from LSKs to MKs with loss in ERY for Itgb3. Displays are arranged as in (a) except RNA-Seq is shown for the plus strand

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