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Fig. 7 | Epigenetics & Chromatin

Fig. 7

From: Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten

Fig. 7

Difference in HiSeq X Ten coverage distribution for FFPET bisulphite library prepared from two methods. a, b Box plot showing the difference in coverage across CpG islands, CpG shores and other regions of the genome for TruMethyl WG (a) and Accel-NGS Methyl-Seq (b) methods, when sequenced on the HiSeq X Ten. c IGV plot showing the difference in distribution of reads for a FFPET library obtained from the TruMethyl WG method and Accel-NGS Methyl-Seq method across a CpG island. d, e Box plots showing the coverage distribution across exons, intergenic regions, introns, promoter regions and repeat regions of the genome for a FFPET library prepared by the TruMethyl WG (d) and Accel-NGS Methyl-Seq (e) methods and sequenced on one lane of HiSeq X Ten

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