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Table 3 Enzymatic complex components in SIN3 histone-modifying complexes in different species

From: Same agent, different messages: insight into transcriptional regulation by SIN3 isoforms

Organism Complex Enzymatic complex component
S. cerevisiae [50] RPD3L RPD3 (Histone deacetylase)
RPD3S RPD3 (Histone deacetylase)
S. pombe [49] Complex I/I’ Clr6 (Histone deacetylase)
Complex II Clr6 (Histone deacetylase)
D. melanogaster [52, 77] SIN3 187 RPD3 (Histone deacetylase)
SIN3 220 RPD3 (Histone deacetylase)
dKDM5/LID (Histone demethylase)
M. musculus [8,9,10, 53] SIN3A HDAC1, HDAC2 (Histone deacetylase)
SIN3B HDAC1, HDAC2 (Histone deacetylase)
RBP2 (Histone demethylase)