TY - JOUR AU - García-Molinero, Varinia AU - García-Martínez, José AU - Reja, Rohit AU - Furió-Tarí, Pedro AU - Antúnez, Oreto AU - Vinayachandran, Vinesh AU - Conesa, Ana AU - Pugh, B. Franklin AU - Pérez-Ortín, José E. AU - Rodríguez-Navarro, Susana PY - 2018 DA - 2018/03/29 TI - The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally JO - Epigenetics & Chromatin SP - 13 VL - 11 IS - 1 AB - Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recruited genome-wide in yeast. However, how this broad recruitment confers selectivity under specific conditions remains an open question. SN - 1756-8935 UR - https://doi.org/10.1186/s13072-018-0184-2 DO - 10.1186/s13072-018-0184-2 ID - García-Molinero2018 ER -