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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis

Fig. 1

Drosophila spermatogenesis and the main regulators of gene activity. a An overview of the first stages of spermatogenesis in Drosophila. Germline stem cell (GSC) divides asymmetrically producing a gonioblast (GB). After four mitotic divisions, a cyst of 16 spermatogonia (SpG) is formed. These differentiate synchronously to spermatocytes (SpC) that replicate their chromosomes and enter meiosis. Mutation in bam gene precludes the differentiation step resulting in accumulation of SpG cysts in the testis. Meiosis arrest mutants fail to proceed to meiosis and accumulate SpC cysts. Gray bars indicate the germline cell types that are presented in the testes of bam or meiosis arrest mutants and contribute to the DamID and expression profiling experiments in this study. b Comparison of tMAC and MMB/dREAM complexes. Two complexes share common components (red) and contain homologous subunits (green). c Comparison of tTAFs and TFIID complexes. Homologous subunits are shown in green. TBP protein associated with tTAFs is unknown

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