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Table 3 Additivity of multiple PTMs

From: Modulation of nucleosomal DNA accessibility via charge-altering post-translational modifications in histone core

  ΔΔG (kcal/mol) for the acetylation of Difference
H3K115 H3K122 H3K115 and H3K122
Experimental data 0.4 ± 0.2 0.2 ± 0.2 0.6 ± 0.2 0.0 ± 0.35
Calculated values 0.2 ± 0.01 0.3 ± 0.01 0.3 ± .0.01 0.2 ± 0.01
  1. Comparison of experimentally determined and calculated ∆∆G for a PTM pair