Skip to main content

Table 3 Additivity of multiple PTMs

From: Modulation of nucleosomal DNA accessibility via charge-altering post-translational modifications in histone core

 

ΔΔG (kcal/mol) for the acetylation of

Difference

H3K115

H3K122

H3K115 and H3K122

Experimental data

0.4 ± 0.2

0.2 ± 0.2

0.6 ± 0.2

0.0 ± 0.35

Calculated values

0.2 ± 0.01

0.3 ± 0.01

0.3 ± .0.01

0.2 ± 0.01

  1. Comparison of experimentally determined and calculated ∆∆G for a PTM pair
Back to article page

Epigenetics & Chromatin

ISSN: 1756-8935