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Table 2 PTMprint classification for all possible acetylations per core histone

From: Modulation of nucleosomal DNA accessibility via charge-altering post-translational modifications in histone core

Classification/histone

H2A

H2B

H3

H4

Change DNA accessibility in entry/exit

K118, K119, K127, K129

K125*

K36, K64

K31

Change DNA accessibility globally

K13, K15, K36

K23, K24, K27, K28, K31, K34, K43, K85

 

K79, K91, H4K77*

Change DNA accessibility in both regions

K74, K75, K125

K46, K57

K27, K37, K56

K44

Weak effect on DNA accessibility

K95

K108, K116, K120

K79, K115, K122

K5, K12, K16, K20, K59

  1. PTMs predicted to have non-weak stabilizing effect on the nucleosome, and thus a decrease in the DNA accessibility, are marked by asterisk
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Epigenetics & Chromatin

ISSN: 1756-8935